Yeah. I have done some experimentation with the Chrome/Firefox/IE problem. well, the Chrome/Firefox problem. IE was never really an option. Anyway, Firefox does rather well with df if it is 'only' doing df, and nothing else. Chrome way outperforms Firefox when using DF, CB, map, and grooveshark all at once. It's got something to do with the way chrome handles it's tabs.
*sparing everyone geeky lecture*
Bottom line, if you don't want any distraction from playing DF, use firefox with no other windows. otherwise, use Chrome.